Magnetic properties: fe3o4 nanoparticles coated with chitosan and gallic acid were characterized by vibrating sample magnetometry. the hysteresis loops as a function of the magnetic field at room temperature. The magnetic parameters, including saturation magnetization and remnant magnetization, The saturation magnetization of the fe3o4 nanoparticles core-shelled by chitosan and gallic acid was about 26.074 emu/g, while the naked fe3o4 was about 29.091 emu/g. The decrease in saturation magnetization was most likely due to the existence of coated materials and impurities on the surface of the magnetic nanoparticles.45 According to the vibrating sample magnetometry results, the nanoparticles showed superparamagnetic behavior, ie, they did not retain any magnetism after removal of the magnetic field. High magnetization and super paramagnetic properties are highly sought after for biomedical applications because the larger magnetic particles form aggregates after exposure to a magnetic field.

      Conclusion: The magnetic nano carrier enhanced the thermal stability of the drug, gallic acid. Release of the active drug from the FCG nano carrier was found to occur in a controlled manner. The gallic acid and FCG nanoparticles were not toxic in a normal human fibroblast (3T3) line, and anticancer activity was higher in HT29 than MCF7 cell lines.