Nano Au for Biomedical Applications

The biomedical field is a brand-new research field formed by integrating the methods and theories of medicine, biology and other related disciplines. Its research contents include bio-medicine, clinical applied chemistry, cytology and immunology, etc. With the rapid development of technology, many cutting-edge research and inventions in hot areas have played an important role in the field of bio-medicine, such as digital holography, virtual reality, and nanotechnology. It can be said that bio-medicine is an important area related to human beings. Studies have shown that surface-modified nano-gold particles can play a very important role in cell imaging, drug carriers, and many other aspects, its performance is closely related to the structure of nano-gold composition, morphology, size and size. More attention is paid to the appearance of gold nano structures such as rods and spheres.

 

Nanomaterials are materials in which at least one dimension in the three-dimensional space is in the nanoscale range or consists of them as basic units. Nano gold is a kind of nano material and is a gold nano particle with a diameter of 1-100nm. Nano-gold particles play an important role in molecular detection, photo-thermal therapy, tumor diagnosis, and green catalysis. In the following, I will give a detailed review of the field of bio-medicine.

 

  1. Application in bio-moleculardetection and identification

The emergence of nano gold immunolabeling technology in 1971 made it possible to see the great potential of nano gold as an immunological marker. After decades of continuous development, the immunolabeling technology using nanogold as a marker has basically matured. Has become one of the four major immunolabeling technologies. With the advancement of science and technology, people have a deeper understanding of the physicochemical properties of Gold nanoparticles dispersion , thus further expanding the biometric detection technology using nano gold as a marker. At present, nanogold is mainly used in biological detection to detect nucleic acids and proteins. Based on its unique surface plasmon resonance effect, catalytic properties, and high-density properties and other physicochemical properties, nano gold has unparalleled advantages in other areas of biological detection, and it has great potential for early diagnosis of tumors.

 

  1. Application in cell imaging and photothermotherapy

The strong scattering of nano gold particles was first used by researchers in the field of nano gold cell imaging and is still the most commonly used nano gold cell imaging method. As long as the diameter of the nano gold particles is greater than 20nm, it can be easily observed in a dark field scattering microscope. Compared with common fluorescent groups, nano gold particles can stably scatter light for a long time without being bleached. At the same time, due to the surface plasmon resonance effect of the nano-gold particles, the molecular electromagnetic field signal will be enhanced if it is within the nano gold surface or within 10 nm from the nano gold surface. Through the extraction of these enhanced electromagnetic field signals, Can be applied to bio-imaging technology. Because nano gold’s two-photon luminescence imaging technology has a much higher signal-to-noise ratio than dark-field microscopy, it has a very high potential for intracellular imaging. In addition, nano-gold particles can produce high thermal behavior by absorbing near-infrared light, a feature that makes it play a significant role in photothermal therapy in medicine.

 

  1. Application in drug delivery and controlled release

The specific surface area of ​​nano gold is relatively large, and its surface is easily modified. The drug can easily bind to the nano gold surface after chemical bonds and non-chemical bonds, thereby forming a nano gold drug-loading system. The drug-loading system formed by nano gold has the characteristics of increasing drug solubility, increasing cytotoxicity, and increasing drug stability. Currently, nano gold has been widely used in various fields of bio-medicine as a carrier for various types of drugs. The use of nano gold as a drug carrier can both protect the drug, increase the activity of the drug, reduce the amount of the drug used, and reduce the medical cost.

Related Tags: Nano gold colloid  Nano Gold dispersion

Carbon nanotubes are used in batteries

Lithium iron phosphate power cell is the most potential lithium-ion power battery for electric vehicles in the market, which has the advantages of good safety, long cycle life, and high energy density. However, lithium iron phosphate has poor electrical conductivity and conductive agent must be added to improve its conductivity. Most commonly used conductive agents are carbon black and graphite, which is cheap. However, in the process of multiple charging and discharging, the expansion and contraction of graphite materials reduces the contact between graphite particles, increases the gap, and even separates from the collector fluid and no longer participates in the electrode reaction. Therefore, the choice of conductive agent has an important role in improving battery performance.
At present, carbon nanotubes(CNTs) have gained wide attention in the application of conductive agents due to their excellent physical and chemical properties. The conductive mechanism of carbon nanotubes is that because they belong to one-dimensional nanomaterials, the length-diameter ratio is relatively large, which is good for the formation of conductive networks, and can improve the bonding between active materials and their collective flow, also it play the role as a physical adhesive. At the same time, it has excellent mechanical properties and chemical inertia, and it also has good thermal conductivity. It can improve the specific capacity and cycle life of the battery and improve the high temperature performance. It is an ideal new type of conductive material for lithium ion batteries.
In the experiment, multi-wall carbon nanotubes were applied to the positive and negative poles of lithium iron phosphate batteries respectively, and different tired batteries were prepared. The conventional performance and doubling rate were tested, and they were compared with the cores prepared by ordinary conductive carbon black. The test results show that, The electric core of high-conductive multi-wall carbon nanotubes added to the carburetor nanotubes has better conventional performance and double discharge performance than the conventional core, and the double discharge effect of both positive and negative poles is the best, followed by the addition of negative poles. The addition of MWCNTs to the negative electrode also shows the same situation. After the negative electrode capacity increases, it can embed more lithium ions when charging, which is conducive to the increase of discharge capacity, and because multi-walled carbon nanotubes have better electronic transport capabilities. In addition, more continuous conductive networks are formed in the click, which reduces the number of active substance particles encouraged. Also, the positive pole is added. The carbon nanotube, in high purity, is easy to disperse, has a low resistivity and can reach a resistivity of 650 μΩ. M, which is very suitable for battery use.
Multi-wall carbon nanotubes for lithium iron phosphate batteries
The addition of carbon nanotubes also has an important influence on the electrochemical performance of lead acid battery negative plates. After adding CNT, it can increase the amount of liquid absorption of the electrode, improve the transmission performance of the electrolyte in holes, and also improve the negative electrode conductivity, enhance the charging and discharging ability, improve the morphology and utilization rate of the active material, and slow down the salt of the negative electrode. In partial charge state, the rapid discharge cycle life of the plate can be extended. The negative electrode is added to the CNT battery prepared by 0.5 % CNT. When the SBAS0101 is rapidly charged and discharged under 50 % charge state, the battery discharge termination voltage is increased and the cycle life is extended.

Related Tags:Transparent Silver Colloid  Colloidal Gold