Dispersion method of nano silver powder

Because of the volume effect, surface effect, quantum size and other effects unique to nanomaterials, nano silver powder has many special uses. In the field of antibacterial medicine, silver nano particles are more likely to be in close contact with pathogenic microorganisms, thereby exerting greater biological effects. It has the characteristics of wide antibacterial range and long duration, and is a new type of nano material with broad application prospects.

 

Nanopowders have small particle size and high surface activity, and it is easy to agglomerate between particles. Ag nano powder is no exception. The agglomeration will affect the development and application of nano Ag particle and its derivatives. The key technology is solve the agglomeration and obtain a stable dispersion. In order to obtain nano silver materials that are compatible with the process formula and are easy to disperse, please refer to the following points:

 

  1. If the user is willing to provide the application details, Hongwu Nano can modify the silver nanowires in advance to improve the dispersion of silver accordingly.
  2. In general, the addition of surfactants and mechanical dispersion methods should be combined to achieve good dispersion effects.
  3. Commonly used mechanical dispersing equipments include: generally used in low viscosity systems such as water and organic solutions, high-speed dispersing machines and ultrasonic equipment can be selected. High-viscosity system (paste) can be selected pulp mill, surface mill, high-speed dispersion disc, ball mill, etc..
  4. The dried silver powder can be depolymerized and surface modified with a supersonic jet mill.
  5. Commonly used surfactants: polymer surfactants such as PVP, gum arabic, polyethylene glycol, polyvinyl alcohol, etc. These dispersants are recommended for water-based systems. Surfactants can be used in combination and can significantly improve the dispersion effect.
  6. Based on years of silver powder production experience and users’ feedback, Hongwu Nano has summed up practical nano silver powder dispersion methods and techniques. Currently we can provide untreated nanosilver powder, surface-modified nano-silver powder, nano-silver water dispersion(colloidalAg), etc. Tailor-made nano-silver series products according to customer requirements.

The Application Of Nano Silver Antibacterial In Clinical Treatment

Nano silver powder is a new type of antibacterial product developed based on nanotechnology. Due to the quantum effect, small size effect and large specific surface area, it has an antibacterial effect that traditional inorganic antibacterial agents can’t match. It has high safety and long-lasting effectiveness. , Is an antibacterial agent with long-lasting and weather resistance.

Regarding the principle of the bactericidal effect of nano-silver, most scholars believe that the specific surface area of ultra-fine silver is very large and presents AG+ in water. Therefore, the bactericidal effect of nano-silver is mainly related to silver ions, which can be related to the -SH in the enzyme protein in the bacteria. It binds quickly to inactivate key metabolic enzymes, making pathogenic bacteria unable to metabolize and die; secondly, nano-silver can bind to DNA bases of pathogenic bacteria and form cross-links to replace hydrogen bonds between adjacent nitrogens in purines and pyrimidines. Which denatures DNA without being able to replicate, leading to inactivation of pathogenic bacteria. The atomic arrangement of nano-silver shows that it is a “medium state” between solid and molecule. This extremely active nano-silver particle has super antibacterial ability and can kill bacteria, fungi, mycoplasma, chlamydia and other pathogenic microorganisms. In addition, nano-silver is a non-antibiotic bactericide, and no bacteria are resistant to nano-silver.

1. Application in burns, scalds, burn skin grafts
The results of skin grafting for dozens of burn patients showed that nano-silver increased the epithelialization rate of reticuloepithelial grafts by 40%, and had a better effect on promoting repair of residual burn wounds. The healing time of the experimental group was significantly shorter than that of the control group. Researchers believe through clinical observations and animal experiments that nano-silver antibacterial medical dressings are a kind of clinical external medicine for burns with strong anti-infective effect, low absorption, small toxic and side effects, and convenient use.

2. Application in dermatology
Nano silver is effective in treating acne vulgaris. The nano-ulcer patch is used to treat I-II bedsores. In comparison with the control, it is found that the active ingredient of the nano-ulcer patch is nano-silver particles, which has super permeability, produces a biothermal effect, improves the microcirculation of the damaged tissue, and eliminates the local area. Edema is conducive to tissue regeneration and wound healing.

3. Application in dentistry
Nano silver antibacterial agent can be used to prevent oral caries and mucosal diseases, and can also solve the problem of easy pollution during the production and use of dental materials.

In summary, due to its quantum effect, small size effect and large specific surface area, nano-silver materials are easily in close contact with pathogenic microorganisms, thereby exerting greater biological effects, so they have high safety, wide antibacterial range, and continuous Advantages such as long sterilization time. However, nano-silver materials are prone to particle aggregation and lose their nano-characteristics under conventional conditions without protective agents, which will affect the antibacterial effect of nano-materials. Therefore, the packaging and storage of nano-silver are also extremely important. For details, please consult Hongwu Nano staff online our website:https://www.hwnanomaterial.com/.

Magical nano silver powder — seven antibacterial characteristics

The nanometer (nm) is the smallest unit of measure after the micron, and the nanometer is one millionth of one millimeter, that is to say, nanometer is one billionth of a meter. Nano silver powder is made through cutting-edge nano-technology. The emergence of silver powder in the nanometer state, promotes a qualitative leap of bactericidal ability, very few nano-silver can produce a strong bactericidal effect. It can kill more than 650 kinds of bacteria in a few minutes, with broad-spectrum sterilization and no resistance, whihc can promote wound healing, cell growth and repair damaged cells, without any toxic reactions, find no any stimulus response to the skin. All this opens up a broad prospect application of antimicrobial of nano silver powders,and become the latest generation of natural antibacterial agents. Nano silver sterilization has the following characteristics:

1. Broad spectrum antimicrobial

Nano-silver particles directly into the cell, work with oxygen metabolism enzyme (-SH), make the bacteria asphyxia and death of the unique mechanism of action, which can kill contact with most of the bacteria, fungi, mold, spores and other microorganisms. It has found that it has comprehensive antibacterial activity against drug resistant pathogens such as Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pyogenes, Enterococcus, and anaerobic bacteria. Fungi such as Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Candida albicans and other G +, G-pathogens have bactericidal effects on Chlamydia trachomatis, causing sexually transmitted diseases. Neisseria gonorrhoeae also has a strong bactericidal effect.
An antibiotic can kill about 6 pathogens, while nanoscale silver can kill hundreds of pathogenic microorganisms. Strong effect to kill bacteria, fungi, trichomoniasis, chlamydia / chlamydia, Neisseria gonorrhoeae, bactericidal, the same effect for antibiotic resistance!

2. Potent sterilization

According to the study, it’s found that Ag can kill more than 650 kinds of bacteria in a few minutes. Nano-silver particles and pathogens after the cell wall / membrane binding, can directly into the cell, quickly with the oxygen metabolism of the enzyme thiol (-SH) binding, the enzyme inactivation, blocking the respiratory metabolism to suffocate. Unique bactericidal mechanism, so that nano-silver particles in the low concentration can quickly kill pathogens.

3. Permeability is strong

Nano-silver particles with superior permeability, can quickly penetrate the skin 2mm sterilization, have a good bactericidal effect on the common bacteria, stubborn bacteria, drug-resistant bacteria and fungi caused by deep tissue infection.

4. Repair regeneration

Nano silver can promote wound healing, promote the repair and regeneration of damaged cells, to rot myogenic, anti-bacterial anti-inflammatory to improve the microcirculation around the wound tissue, effectively activate and promote tissue cell growth, accelerate wound healing, reduce scar generation.

5. Antibacterial lasting

Nano-silver particles using patented technology, a layer of protective film, in the human body can be gradually released, so antibacterial effect

6. Safe and non-toxic

As early as the “Compendium of Materia Medica” records: raw silver, non-toxic; US Public Health Bureau in 1990, “on the toxicity of silver investigation report” that: silver on the human body no obvious side effects; nano silver is topical, Is the safest way to use it. According to the experimental study found that mice in the oral maximum tolerance of 925mg / kg, which is equivalent to the clinical use of 4625 times the dose, without any toxic reactions in the rabbit skin irritation experiments, did not find any stimulus response.

7. No drug resistance

Nano-silver is non-antibiotic fungicide: nano-silver can kill a variety of pathogenic microorganisms, stronger than antibiotics, 10nm size of nano-silver particles unique antibacterial mechanism can quickly kill bacteria directly to the loss of reproductive capacity, therefore, can not produce Drug resistance of the next generation, can effectively avoid the resistance caused by recurrent long-term treatment.

Hongwu Nano, an expert in manufacturering in nanopowders since 2002, especialy nano Silver powders with the best antibacterial property.
High purity,99.99%, good shape,spherical, uniform particle size, easy to disperse nano silver powders are supplied.
Generally speaking, the smaller particle size of Ag nanoparticles, the better bactericidal effect.
Silver nanopowders can not only be available for powders state, but also nano silver antibacterial solution, which is ready to be used, is available.
The concentration of nano silver antibacterial solution is 1000PPM commonly. Other concentration of the solution can be customized.

Related Tags:silver nanoparticles antimicrobial   silver nanoparticles applications in medicine

Silver nanopowder for antibacterial

Antibacterial mechanism of nano silver powder

Nano-silver particles can enter inside the micro-organisms, interrupt RNA replication to stop it’s reproduction , meanwhile it attached to the microbial cell wall, the impact of microbial organisms transmission finally cause the cell’s rupture and death.

Advantage of nano silver powder in antibacterial application

1) Disinfection and sterilization effect is good, lasting and have no drug resistance problem.

2) small amount at ppm level nano-silver antimicrobial products means lower cost.

3) without shortcoming of allergies and excessive deposition as traditional silver salt antibacterial agent do.

4) non-toxic to human safety, environmentally friendly.

 

Speak of nano silver powder, it’s like a far away high-technology topic, but speaking of specific, detailed antibacterial applications, we know nano silver particle can be part of our daily life.

 

  1. Food

No doubt people consume food every day, and silver nano particle could take pat in our daily life in the way of antibacterial food container. Since nano silver have an inhibitory effect on the common food contamination bacteria (Gram-positive bacteria, Gram-negative bacteria, yeast, mold, etc.), it is applied to produce antibacterial food containers: nano silver food crisper, nano silver plastic wrap, antibacterial ceramic tableware, antibacterial refrigerator

 

  1. Clothing

Nano silver’s antibacterial works as well as on fabrics, try search nano silver antibacterial socks on your online purchasing platforms, there surly comes out lot of results. In fact, some researchers does experiments and proves that nano silver particle function more than merely antibacterial part, also fabrics’’ anti-static and far infrared performance is also improved by nano silver finishing.

 

  1. Living

Nano silver is also widely used in building materials: Nano silver antibacterial coatings, nano-silver antibacterial paint, etc., they are coated on the surface of the plate can kill the surface attached bacteria, and the antibacterial effect is lasting.

 

  1. Medicine

No doubt that antibacterial work is more critical when it comes to the matter of health. And yes nowadays nano silver particle is maturely applied into medicines. For example: nano silver antibacterial dressings, nano silver antibacterial gel, nano silver antibacterial catheter, nano silver antibacterial equipment, nano silver bone cement, etc. I cannot list them all.

 

Related reading:nano silver antimicrobial   antimicrobial silver nanoparticles