Results of Magnetic Nano-iron Striking Glioma Treatment
Nano-iron, iron magnetic nanoparticles,
nano-iron manufacturers
Hyperthermia is a type of glioma using a variety of physical energy (such as
microwave, radio frequency and ultrasound) to produce thermal effects in glioma
tissues, so glioma tissue temperature reaches 41-43 degrees Celsius effective
treatment temperature, and maintain certain period of time (usually 30
minutes), to destroy the tumor cells metabolism, accelerate the apoptosis of
tumor cells but not in normal brain tissue without damage methods.
Magnetic nano iron is an alternating magnetic field capable of rapid warming of
nanomaterials. Tc is the Curie temperature of a magnetic field in some of the
material to non-magnetic critical temperature. When the temperature is less
than Tc, the ferromagnetic substance is shown, it is strongly absorbed
electromagnetic energy to heat up. When the temperature is higher than Tc, they
turned into non-magnetic material, the loss of the ability to absorb
electromagnetic energy to heat up. Magnetic nano iron is a material having a
lower TC. When the magnetic nano-iron stereotactic injection of rat glioma, due
to hysteresis, relaxation effects, the domain wall resonance effect, under the
irradiation of an external magnetic field can strongly absorb electromagnetic
energy and temperature to 41-43 degrees Celsius, and can steady for 30 minutes,
promote tumor cell apoptosis and inhibit the proliferation of tumor, and the
smaller surrounding normal brain tissue damage.
At
present, although the nano iron hyperthermia glioma impressive results, but
overall still in the research stage in vitro and in animal experiments. The
modified magnetic iron nanoparticles can cross the blood, after so after intravenous
injection, by active and passive accumulation in tumor targeting areas, can
greatly improve the tumor area magnetic nano iron concentration, enhance the
efficacy and minimize normal tissue injury. Meanwhile, the modified magnetic
nanoparticles can carry iron ligand specificity, binding to a specific tumor
cell surface receptor, the nano-iron, and precisely to reach the stable area ofa solid tumor stays. Modified nano-iron can also carry chemotherapy
drugs, tumor hyperthermia and chemotherapy simultaneously. Magnetic nano iron
hyperthermia, chemotherapy, radiotherapy for the treatment of cancer and other
comprehensive orientation will become glioma therapy.
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